Ideas

Probiotic comes to the rescue of blood-stage Plasmodium infection: Probiotic Bifidobacterium adolescentis IM38 decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clears blood-stage malaria, via up regulation of its target gene, 28/February/2019, 7.26 am
Probiotic comes to the rescue of blood-stage Plasmodium infection: Probiotic Bifidobacterium adolescentis IM38 decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clears blood-stage malaria, via up regulation of its target gene, 28/February/2019, 7.26 am 960 720 Dr Boomi's Genom-2-Discovery Center

National Science day special ********* We wish everyone a very happy national science day. On this special occasion, we are happy to announce that Bio-Med/Pharma/Therapeutic/Clinical ideas posted today (28/February/2019) will be…

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Probiotics-based adjunctive therapy for Malaria: A probiotic mixture(LB+LC) encompassing Lactobacillus plantarum KY1032 and Lactobacillus curvatus HY7601 increases Ferroportin expression, decreases intracellular iron accumulation, inhibits cellular damage, prevents hemolysis, and inhibits malaria infection, via upregulation of its target gene, 28/February/2019, 7.04 am
Probiotics-based adjunctive therapy for Malaria: A probiotic mixture(LB+LC) encompassing Lactobacillus plantarum KY1032 and Lactobacillus curvatus HY7601 increases Ferroportin expression, decreases intracellular iron accumulation, inhibits cellular damage, prevents hemolysis, and inhibits malaria infection, via upregulation of its target gene, 28/February/2019, 7.04 am 960 720 Dr Boomi's Genom-2-Discovery Center

National Science day special ********* We wish everyone a very happy national science day. On this special occasion, we are happy to announce that Bio-Med/Pharma/Therapeutic/Clinical ideas posted today (28/February/2019) will be…

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Repurposing the known anti-HIV drug into a stroke medicine: Maraviroc, an anti-HIV drug, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits, via up-regulation of its target genes BDNF and NAMPT, 27/February/2019, 4.05 am
Repurposing the known anti-HIV drug into a stroke medicine: Maraviroc, an anti-HIV drug, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits, via up-regulation of its target genes BDNF and NAMPT, 27/February/2019, 4.05 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; and School of Public…

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Combinatorial therapy for Deafness: A therapeutic mix encompassing Fenofibrate, Cholecalciferol, Ajoene and DIM (FCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via upregulation of its target genes, 27/February/2019, 7.29 am
Combinatorial therapy for Deafness: A therapeutic mix encompassing Fenofibrate, Cholecalciferol, Ajoene and DIM (FCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via upregulation of its target genes, 27/February/2019, 7.29 am 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Combinatorial therapy for Deafness: A therapeutic mix encompassing Fenofibrate, Cholecalciferol, Ajoene and DIM (FCAD)  increases the expression of ATG5 (Autophagy-related 5),…

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Cholecalciferol-based therapy for glaucoma:  1α, 25 (OH)2D/Cholecalciferol/Calcitriol  increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma,  via down regulation of its target gene, 26/February/2019, 8.50 am
Cholecalciferol-based therapy for glaucoma:  1α, 25 (OH)2D/Cholecalciferol/Calcitriol  increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma,  via down regulation of its target gene, 26/February/2019, 8.50 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, USA; The Howard Hughes…

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Natural product-based therapy for inflammation and arthritis: Oridonin, found in Rabdosia Rubescens, increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis,  via up-regulation of its target genes, 26/February/2018, 8.40 am
Natural product-based therapy for inflammation and arthritis: Oridonin, found in Rabdosia Rubescens, increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis,  via up-regulation of its target genes, 26/February/2018, 8.40 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that “Resolution of inflammation by…

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