CTB-UE vaccine-based therapy for autoimmune diabetes (TIDM):  CTB-UE vaccine, known to eradicate infections caused by H. pylori,  increases the expression of PD-L1, augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 12/July/2018, 11.14 pm