Molecular therapy for aging-associated diseases and Lifespan extension: Prostaglandin D2 (PGD2), the principal cyclooxygenase (COX2) metabolite of arachidonic acid, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging via down-regulation of its target gene, 27/November/2018, 6.29 am