Molecular therapy for Bone disorders: MiR-188 inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 27/November/2016, 8.10 pm

Molecular therapy for Bone disorders: MiR-188 inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 27/November/2016, 8.10 pm

Molecular therapy for Bone disorders: MiR-188 inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 27/November/2016, 8.10 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say

A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.”

This study was published in the June 25, 2014 Nature  [I.F >42] by Prof. Wan Y, Krzeszinski and others from  the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.


What we say:

On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Molecular therapy for Bone disorders: MiR-7-3p inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene.[easy_payment currency=”USD”]

price-100


From Research findings to Therapeutic utility

MiR-188, by down-regulating its target gene, it may suppress the expression of Tgif2. Thereby, it may inhibit the progression of Osteoporosis and bone metastasis. Thus, pharmacological formulations encompassing “MiR-188 or its activators” can be used to inhibit osteoporosis and bone metastasis.


Details of the research findings

Idea Formulated (with experimental evidence) by: Dr L Boominathan PhD

Undisclosed information: How MiR-188 suppresses the expression of Tgif2

Amount: $100#

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 Reference:

CitationBoominathan, L., Molecular therapy for Bone disorders: MiR-188 inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 27/November/2016, 8.10 pm., Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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