Neuropeptide-based therapy for blood sugar disease (autoimmune diabetes (TIDM)):  Neuropeptide (NPY), a 36 amino-acid neuropeptide known to play a role in food intake and weight determination,  increases PD-L1 expression,  augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 12/April/2018,  11.50 pm