Molecular therapy for safeguarding your heart against cardiac dysfunction: Canagliflozin (trade name: Invokana or Sulisent), a drug used in the treatment of TIIDM,  decreases tumor suppressor Mir-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up-regulation of its target gene, 15/November/2018, 10.02 pm