Act(os) for an enhanced, extended, and healthy-lifespan: Pioglitazone (trade name: Actos), an anti-hyperglycemic agent, increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 29/August/2018, 8.09 am