Ideas

Natural product-based Lifespan extension therapy:  Diosgenin, derived from Dioscorea,  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan by regulating the expression of its target genes, 17/July/2019, 11.10 pm
Natural product-based Lifespan extension therapy:  Diosgenin, derived from Dioscorea,  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian lifespan by regulating the expression of its target genes, 17/July/2019, 11.10 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1…

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Where eating the peel will protect you against viral diseases than the pulp (fruit): Citrus peel-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Hesperidin, Tangeretin & Nobiletin (HTN), isolated from citrus flavonoid purity mixture or citrus peels, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via upregulation of its target gene, 17/July/2019, 10.40 pm
Where eating the peel will protect you against viral diseases than the pulp (fruit): Citrus peel-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Hesperidin, Tangeretin & Nobiletin (HTN), isolated from citrus flavonoid purity mixture or citrus peels, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via upregulation of its target gene, 17/July/2019, 10.40 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

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Probiotics as Longevity-promoters: The tiny probiotic may increase the lifespan of mighty humans: Probiotic-based therapy for aging-associated diseases and Lifespan extension: Probiotic Bifidobacterium animalis subsp.lactis LKM512 inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 17/July/2019, 10.10 pm
Probiotics as Longevity-promoters: The tiny probiotic may increase the lifespan of mighty humans: Probiotic-based therapy for aging-associated diseases and Lifespan extension: Probiotic Bifidobacterium animalis subsp.lactis LKM512 inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 17/July/2019, 10.10 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and Department of Pharmacology, School…

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Probiotics as Analgesics: Probiotic bifidobacterium animalis subsp. lactus LKM512  functions as a pain reliever: Mechanistic insights into how Probiotic bifidobacterium animalis subsp. lactus LKM512  functions as a pain medication: Probiotic bifidobacterium animalis subsp. lactus LKM512  increases the expression of PD-L1, TRPV1, and CGPR, decreases the expression of Cox-2, attenuates acutes and chronic pain, headache, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 17/July/2019, 11.51 am
Probiotics as Analgesics: Probiotic bifidobacterium animalis subsp. lactus LKM512  functions as a pain reliever: Mechanistic insights into how Probiotic bifidobacterium animalis subsp. lactus LKM512  functions as a pain medication: Probiotic bifidobacterium animalis subsp. lactus LKM512  increases the expression of PD-L1, TRPV1, and CGPR, decreases the expression of Cox-2, attenuates acutes and chronic pain, headache, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 17/July/2019, 11.51 am 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

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Surgery to mitigate complications of diabetes and obesity comes of age: Mechanistic insights into how Roux-en-Y gastric bypass (RYGB) surgery can save you from blood sugar disease (Diabetes Mellitus): Roux-en-Y gastric bypass (RYGB), one of the bariatric surgical procedure performed for weight loss,  augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM, via upregulation of its target gene, 15/July/2019, 7.41 am
Surgery to mitigate complications of diabetes and obesity comes of age: Mechanistic insights into how Roux-en-Y gastric bypass (RYGB) surgery can save you from blood sugar disease (Diabetes Mellitus): Roux-en-Y gastric bypass (RYGB), one of the bariatric surgical procedure performed for weight loss,  augments the expression of FGF19 and FGF1,  attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIDM, via upregulation of its target gene, 15/July/2019, 7.41 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection of FGF1 induces sustained…

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Small molecule-based Lifespan extension comes of age-β-guanidinopropionic acid (β-GPA) aids in Lifespan extension: β-guanidinopropionic acid (β-GPA) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, increases adult stem cell proliferation, alleviates ageing feature and extends lifespan, via upregulation of its target genes ATG5 (Autophagy-related 5) and telomerase, 15/July/2019, 10. 6.31 am
Small molecule-based Lifespan extension comes of age-β-guanidinopropionic acid (β-GPA) aids in Lifespan extension: β-guanidinopropionic acid (β-GPA) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, increases adult stem cell proliferation, alleviates ageing feature and extends lifespan, via upregulation of its target genes ATG5 (Autophagy-related 5) and telomerase, 15/July/2019, 10. 6.31 am 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was published, in the online…

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