Ideas

Molecular therapy for body weight control, energy homeostasis and TIIDM:Docosahexaenoic acid (DHA) inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 3/January/2017, 9.34 am
Molecular therapy for body weight control, energy homeostasis and TIIDM:Docosahexaenoic acid (DHA) inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 3/January/2017, 9.34 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator of adipose insulin resistance.”…

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Natural product-derived PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy in Glioblastoma: A therapeutic mix encompassing Geldanamycin, 5-Azacitidine, Temozolomide, Cerivastatin, Salinomycin, &, Fluoxetine (GATCSF) inhibits oncoproteins EGFR, and Bcl-xl expression, increases tumor suppressor p53 expression, inhibits glioblastoma proliferation, increases interferon-IFNγ signalling, increase antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 3/January/2018, 9.23 am
Natural product-derived PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy in Glioblastoma: A therapeutic mix encompassing Geldanamycin, 5-Azacitidine, Temozolomide, Cerivastatin, Salinomycin, &, Fluoxetine (GATCSF) inhibits oncoproteins EGFR, and Bcl-xl expression, increases tumor suppressor p53 expression, inhibits glioblastoma proliferation, increases interferon-IFNγ signalling, increase antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 3/January/2018, 9.23 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Department of Molecular and Medical Pharmacology, David Geffen UCLA School of Medicine, Los Angeles, California, USA; Jonsson Comprehensive Cancer Center, David Geffen UCLA…

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Vitamin-based regenerative therapy for reversing diabetes: A pharmaceutical mixture encompassing  Pyridoxamine, Calcitriol, Folic acid, and Ascorbic acid (PMCFAAA) increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 1/January/2018, 4.20 pm
Vitamin-based regenerative therapy for reversing diabetes: A pharmaceutical mixture encompassing  Pyridoxamine, Calcitriol, Folic acid, and Ascorbic acid (PMCFAAA) increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 1/January/2018, 4.20 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, California, USA; and Koch Institute…

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Natural product-based Lifespan extension therapy: A pharmaceutical mixture encompassing Chrysin and α-linoleic acid increases life span via up-regulation of its target gene BubR1, 1/January/2018, 9.00 am
Natural product-based Lifespan extension therapy: A pharmaceutical mixture encompassing Chrysin and α-linoleic acid increases life span via up-regulation of its target gene BubR1, 1/January/2018, 9.00 am 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Molecular therapy for inflammation and arthritis: A pharmaceutical mixture encompassing Calcitriol and  TNF-α (CAT)  increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 1/January/2018, 8.46 am
Molecular therapy for inflammation and arthritis: A pharmaceutical mixture encompassing Calcitriol and  TNF-α (CAT)  increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up-regulation of its target genes, 1/January/2018, 8.46 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that “Resolution of inflammation by…

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Natural product therapy for pulmonary arterial hypertension: α-Linoleic acid, isolated from Flax seeds, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 1/January/2018, 5.41 am
Natural product therapy for pulmonary arterial hypertension: α-Linoleic acid, isolated from Flax seeds, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 1/January/2018, 5.41 am 960 720 Dr Boomi's Genom-2-Discovery Center

What they say:  A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November  2009 issue of the journal “Nature Medicine”[the number 1 journal in…

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