Ideas

Natural product-based therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing  α-linoleic acid, Epicatechin and Matrine (LAEM)  inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 1/January/2018, 5.23 am
Natural product-based therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing  α-linoleic acid, Epicatechin and Matrine (LAEM)  inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 1/January/2018, 5.23 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for Cardiovascular Research (DZHK) partner…

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Natural product-based Lifespan extension therapy: A pharmaceutical mixture (LA) encompassing Luteolin and Apigenin, isolated from Salvia and chamomile,  respectively, may increase life span via up-regulation of its target gene BubR1, 31/December/2017, 1.13 am
Natural product-based Lifespan extension therapy: A pharmaceutical mixture (LA) encompassing Luteolin and Apigenin, isolated from Salvia and chamomile,  respectively, may increase life span via up-regulation of its target gene BubR1, 31/December/2017, 1.13 am 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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 Natural product-based antiviral therapy: Resveratrol, a longevity-promoting compound, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytical ,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 31/December/2017,  12.36 am
 Natural product-based antiviral therapy: Resveratrol, a longevity-promoting compound, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytical ,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 31/December/2017,  12.36 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Vitamin B-based therapy for TIIDM and obesity-associated metabolic deficits: A therapeutic mix (PMFA) encompassing Pyridoxamine (PM) and Folic acid (FA) increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 30/December/2017, 11.21 pm
Vitamin B-based therapy for TIIDM and obesity-associated metabolic deficits: A therapeutic mix (PMFA) encompassing Pyridoxamine (PM) and Folic acid (FA) increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 30/December/2017, 11.21 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent suppression of appetite by…

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Natural product-derived regenerative therapy for reversing diabetes: A pharmaceutical mixture encompassing Luteolin, Apigenin and Loureirin B (LALB) increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 30/December/2017, 10.56 pm
Natural product-derived regenerative therapy for reversing diabetes: A pharmaceutical mixture encompassing Luteolin, Apigenin and Loureirin B (LALB) increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 30/December/2017, 10.56 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, California, USA; and Koch Institute…

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Lifespan extension therapy: Acacedin, isolated from Damiana, among others, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 29/December/2017, 11.41 pm
Lifespan extension therapy: Acacedin, isolated from Damiana, among others, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 29/December/2017, 11.41 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown that disruption of AT1R (AGTR1)…

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