Ideas

Activation of the PD-1 pathway for Pain therapy: Diclofenac, a drug used in the treatment of osteoarthritis and migraine,  increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 29/December/2017, 12.10 am
Activation of the PD-1 pathway for Pain therapy: Diclofenac, a drug used in the treatment of osteoarthritis and migraine,  increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 29/December/2017, 12.10 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain Science, Fudan University, Shanghai,…

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Molecular therapy for TIIDM and Metabolic defects: A pharmaceutical mixture (PMEA) encompassing Pyridoxamin (PM) and Etacrynic acid (EA)  increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 29/December/2017, 12.03 am
Molecular therapy for TIIDM and Metabolic defects: A pharmaceutical mixture (PMEA) encompassing Pyridoxamin (PM) and Etacrynic acid (EA)  increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 29/December/2017, 12.03 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27701, USA; Department of…

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Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Ketoconazol, an anti-fungal drug, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 28/December/2017, 11.52 pm
Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Ketoconazol, an anti-fungal drug, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 28/December/2017, 11.52 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

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Natural product therapy for body weight control, energy homeostasis and TIIDM:  A pharmaceutical mixture[PMEA] encompassing Pyridoxamine (PM) and Etacrynic acid (EA)  decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 28/December/2017, 1.21 am
Natural product therapy for body weight control, energy homeostasis and TIIDM:  A pharmaceutical mixture[PMEA] encompassing Pyridoxamine (PM) and Etacrynic acid (EA)  decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 28/December/2017, 1.21 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule1.”…

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Combinatorial Antiviral Therapy (CAT): Chloroquine, an antimalarial drug, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytical ,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 28/December/2017,  1.11 am
Combinatorial Antiviral Therapy (CAT): Chloroquine, an antimalarial drug, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytical ,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 28/December/2017,  1.11 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Lifespan extension therapy: Hydralazine[Trade name: Apresoline], used in the treatment of high blood pressure and heart attacks,  increases life span via up-regulation of its target gene BubR1, 28/December/2017, 1.03 am
Lifespan extension therapy: Hydralazine[Trade name: Apresoline], used in the treatment of high blood pressure and heart attacks,  increases life span via up-regulation of its target gene BubR1, 28/December/2017, 1.03 am 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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