Ideas

Natural product-based Anti-ageing and Life extension therapy:  A pharmaceutical mixture encompassing Apigenin and Chrysin increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 28/December/2017, 12.54 am
Natural product-based Anti-ageing and Life extension therapy:  A pharmaceutical mixture encompassing Apigenin and Chrysin increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 28/December/2017, 12.54 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, University of Cologne, Joseph-Stelzmann…

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Natural product therapy for body weight control, energy homeostasis and TIIDM:Lycopene, isolated from Gac, Guava and Tomatoes,  decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 27/December/2017, 12.20 am
Natural product therapy for body weight control, energy homeostasis and TIIDM:Lycopene, isolated from Gac, Guava and Tomatoes,  decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 27/December/2017, 12.20 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule1.”…

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Natural product-based therapy for TIIDM: A pharmaceutical mixture encompassing Carnosic acid, Lycopene, Ferulic acid, and Glycyrrhizic acid (CALFAG) augments the expression of FGF19 and FGF1,   attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIIDM via up regulation of its target gene, 26/December/2017, 11.59 pm
Natural product-based therapy for TIIDM: A pharmaceutical mixture encompassing Carnosic acid, Lycopene, Ferulic acid, and Glycyrrhizic acid (CALFAG) augments the expression of FGF19 and FGF1,   attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIIDM via up regulation of its target gene, 26/December/2017, 11.59 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection of FGF1 induces sustained…

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Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients:  A pharmaceutical mixture [PMEET] encompassing Pyridoxamine (PM-a form of Vitamin-B (6)) and 14, 15 Epoxyeicosatrienoic acid (14, 15-EET)  increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes via down regulation of its target gene, 26/December/2017, 11.49 pm
Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients:  A pharmaceutical mixture [PMEET] encompassing Pyridoxamine (PM-a form of Vitamin-B (6)) and 14, 15 Epoxyeicosatrienoic acid (14, 15-EET)  increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes via down regulation of its target gene, 26/December/2017, 11.49 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was published, in the 6 April…

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Natural product therapy for Non-alcoholic fatty liver disease (NAFLD): Lycopene, isolated from Gac, Guava and Tomato,  promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 26/December/2017, 11.37 pm
Natural product therapy for Non-alcoholic fatty liver disease (NAFLD): Lycopene, isolated from Gac, Guava and Tomato,  promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 26/December/2017, 11.37 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to 100 million people in…

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Molecular therapy for blood-stage Plasmodium infection: Ribavirin, an anti-viral drug, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via up regulation of its target gene, 26/December/2017, 7.53 am
Molecular therapy for blood-stage Plasmodium infection: Ribavirin, an anti-viral drug, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via up regulation of its target gene, 26/December/2017, 7.53 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that “Regulatory T cells impede…

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