Ideas

Lifespan extension therapy: Lycopene, the commonly found Carotene in Gac, Guava, and Tomatoes, among others, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 26/December/2017, 7.44 am
Lifespan extension therapy: Lycopene, the commonly found Carotene in Gac, Guava, and Tomatoes, among others, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 26/December/2017, 7.44 am 960 720 Dr Boomi's Genom-2-Discovery Center

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown that disruption of AT1R (AGTR1)…

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Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing  N-Acetyl Serotonin, Catalpol, Cholecalciferol, Maresin, Ursolic acid, DIM, Isoliquiritigenin, & Lutein   (NASCCMUDIL) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 26/December/2017, 7.31 am
Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing  N-Acetyl Serotonin, Catalpol, Cholecalciferol, Maresin, Ursolic acid, DIM, Isoliquiritigenin, & Lutein   (NASCCMUDIL) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 26/December/2017, 7.31 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was published, in the online…

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Lifespan extension therapy: Rosmarinic acid, isolated from Rosmarinus officinalis and among others, increases life span via up-regulation of its target gene BubR1, 26/December/2017, 7.08 am
Lifespan extension therapy: Rosmarinic acid, isolated from Rosmarinus officinalis and among others, increases life span via up-regulation of its target gene BubR1, 26/December/2017, 7.08 am 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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 Combinatorial Antiviral Therapy (CAT): Troglitazone, a blood-glucose lowing drug, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytical ,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 26/December/2017,  6.13 am
 Combinatorial Antiviral Therapy (CAT): Troglitazone, a blood-glucose lowing drug, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytical ,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 26/December/2017,  6.13 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Combinatorial therapy for Diabetic retinopathy:  A pharmaceutical mixture encompassing 14, 15, Epoxyeicosatrienoic  acids (14, 15 EETs), Epicatechin, and Matrine (14, 15, EETEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 25/December/2017, 1.56 am
Combinatorial therapy for Diabetic retinopathy:  A pharmaceutical mixture encompassing 14, 15, Epoxyeicosatrienoic  acids (14, 15 EETs), Epicatechin, and Matrine (14, 15, EETEM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 25/December/2017, 1.56 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for Cardiovascular Research (DZHK) partner…

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Molecular therapy for middle aged TIIDM patients: Verapamil, an anti-hyperglycemic medication, decreases DNA-PPK expression, suppresses phosphorylation of HSP90a, increases AMPK activity, augments mitochondrial biogenesis and energy metabolism, promotes weight loss and exercise endurance and alleviates TIIDM via down regulation of its target gene, 25/December/2017, 1.46 am
Molecular therapy for middle aged TIIDM patients: Verapamil, an anti-hyperglycemic medication, decreases DNA-PPK expression, suppresses phosphorylation of HSP90a, increases AMPK activity, augments mitochondrial biogenesis and energy metabolism, promotes weight loss and exercise endurance and alleviates TIIDM via down regulation of its target gene, 25/December/2017, 1.46 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Laboratory of Obesity and Aging Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA; and Laboratory…

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