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Ideas

April 10, 2017

Natural product-derived therapy for prostate cancer bone metastasis: Kukoamine A (KuA), a spermine alkaloid derived from Cortex lycii radicis and Lycium chinense among others, inhibits the expression of Monoamine oxidase A (MAOA), inhibits Shh-IL6-RANKL signaling network, suppresses tumor-stromal interactions, reduces prostate cancer metastasis and prolongs survival via up regulation of its target gene, 11/April/2017, 12.01 am

Introduction: What they say: A study from the Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA shows that “MAOA-Dependent Activation of […]
April 10, 2017

Natural product-derived therapy for Human cancers: α-Lipoic acid, found in leafy green vegetables, increases the expression of mitochondrial protein LACTB, decreases levels of mitochondrial phosphatidylserine decarboxylase, alters mitochondrial lipid metabolism, and promotes differentiation of breast cancer cells via up-regulation of its target gene, 10/April/2017, 11. 45 pm

Introduction: What they say: A study from the Whitehead Institute for Biomedical Research, 9 Cambridge Center, Cambridge, Massachusetts, USA, Department of Biology, Massachusetts Institute of Technology, […]
April 10, 2017

Natural product-derived therapy for Allergic rhinitis:Dioscin, a natural steroid saponin, inhibits GM-CSF, Interleukin 13 receptor(IL-13)-Rα1, and eotaxin expression, among others, inhibits mucus production and alleviates allergic rhinitis via up regulation of its target gene, 10/April/2017, 11.29 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived therapy for Allergic rhinitis: Dioscin, a natural steroid saponin,  inhibits GM-CSF, Interleukin 13 receptor(IL-13)-Rα1, […]
April 10, 2017

Natural product-derived regenerative therapy for reversing diabetes: Berberine, found in Berberis, Oregon grape, Hydrastis canadensis, and Phellodendron amurense among others, increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 10/April/2017, 11.18 pm

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, […]
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