Ideas

September 21, 2017

Published by admin_auro at September 21, 2017

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Lifespan extension therapy: Verapamil, a blood pressure lowering medication, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 22/September/2017, 12.06 am

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]

September 21, 2017

Published by admin_auro at September 21, 2017

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Natural product-based Anti-ageing and Life extension therapy: A pharmaceutical mixture encompassing Naringenin, Astaxanthin, alpha-Tocopherol, Ergothioneine (NATE) increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 21/September/2017, 11.57 pm

Introduction: What they say A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str. Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]

September 21, 2017

Published by admin_auro at September 21, 2017

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Antiviral therapy for Hepatitis-B virus: Sodium Selenite increases the expression of Setd2, methylates STAT1, activates STAT1, promotes trimethylation of IFN-stimulated gene-15, and restricts Hepatitis-B virus (HBV) production and pathogenesis via up regulation of its target gene, 21/September/2017, 10.41 pm

Introduction: What they say A study from the Institute of Immunology, Zhejiang University School of Medicine, Hangzhou 310058, China; and Institute of Immunology, Zhejiang University School […]

September 21, 2017

Published by admin_auro at September 21, 2017

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Ideas
Pain

PD-1 pathway activation for Pain therapy: Fluoxetine, the widely used drug in the treatment of depression, mood disorders among others, increases the expression of PD-L1, attenuates acutes and chronic pain, suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gen, 21/September/2017, 10.30 pm

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]