Ideas

Natural product-derived therapy for Human Leukemias: γ-Bisabolene, one of the components in Cardamom, Cubeb, lemon, and Oregano among others, suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 11/December/2016, 11.07 pm
Natural product-derived therapy for Human Leukemias: γ-Bisabolene, one of the components in Cardamom, Cubeb, lemon, and Oregano among others, suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 11/December/2016, 11.07 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms by which MiR-125b represses IRF4 to…

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Natural product Life-extension therapy: Cucurbitacin E, found abundantly in Watermelons, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 11/December/2016, 7.31 pm
Natural product Life-extension therapy: Cucurbitacin E, found abundantly in Watermelons, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 11/December/2016, 7.31 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say? A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase…

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Natural product-derived Lifespan extension therapy: Saponin, found in Panax Japonicus and Soapworts among others, increases life span via up-regulation of its target gene BubR1, 11/December/2016, 7.07 pm
Natural product-derived Lifespan extension therapy: Saponin, found in Panax Japonicus and Soapworts among others, increases life span via up-regulation of its target gene BubR1, 11/December/2016, 7.07 pm 150 150 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Natural product-derived therapy for Human Leukemias: Eriocitrin, found in lemons, suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 10/December/2016, 11.56 pm
Natural product-derived therapy for Human Leukemias: Eriocitrin, found in lemons, suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 10/December/2016, 11.56 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms by which MiR-125b represses IRF4 to…

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Natural product-derived therapy for Human Leukemias: Ganoderma lucidum suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 10/December/2014, 11.48 pm
Natural product-derived therapy for Human Leukemias: Ganoderma lucidum suppresses B-Cell and myeloid leukemias via up regulation of the tumor suppressor IRF4, 10/December/2014, 11.48 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: Noble laureate in Physiology/Medicine (1975) Prof. David Baltimore, from California Institute of Technology, California, USA, had reported in the July 8, 2014 issue of the Journal “Blood” that: “Dual mechanisms by which MiR-125b represses IRF4 to…

read more

Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: MyoD increases the expression of tumor suppressor p53 homologue TA-p73/p63, PTEN, TPM1, TIMP3, BTG2, PDCD4, SPRY1/2 and CCM1/KRIT1 and induces regression of p53-mutated human tumors via down regulation of its target gene, 10/December/2016, 11.18 pm
Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: MyoD increases the expression of tumor suppressor p53 homologue TA-p73/p63, PTEN, TPM1, TIMP3, BTG2, PDCD4, SPRY1/2 and CCM1/KRIT1 and induces regression of p53-mutated human tumors via down regulation of its target gene, 10/December/2016, 11.18 pm 150 150 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance: Given that: (1) Cancer suppressor p53 is mutated in more than 50% of human cancers of different tissue origin; (2) p53…

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