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Ideas

March 3, 2017

Amino acid therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: L-Leucine, an essential amino acid, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of its target gene, 3/March/2017, 7.31 am

Introduction: What they say:  A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The […]
March 3, 2017

Molecular therapy for Metastatic cancers: Prodigiosin decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up regulation of its target gene, 3/March/2017, 5.57 am

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
March 2, 2017

Amino acid based therapy for glucose homeostasis and TIIDM: Leucine, an essential amino acid found abundantly in parmesan cheese, soy, and hemp seeds and among others, increases Barr2 expression, augments the functional activity of CAMKII, increases insulin secretion, promotes glucose homeostasis, prevents progression to TIIDM and ameliorates obesity-associated metabolic deficits via down regulation of its target gene, 2/March/2017, 10.29 pm

Introduction: What they say A study from the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland […]
March 2, 2017

Natural product-derived therapy for Myocardial Infarction: Withaferin A (WA), isolated from Ashwagantha, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 2/March/2017, 7.21 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
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