Ideas

August 18, 2017

Published by admin_auro at August 18, 2017

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Molecular therapy for inflammation and arthritis: Auranofin increases IL-9 levels, augments proliferation of ILC2s (type 2 innate lymphoid cells) and regulatory T (Treg) cells, promotes resolution of inflammation, attenuates cartilage destruction, decreases bone loss, and inhibits pathological features associated with arthritis via up regualtion of its target genes, 18/August/2017, 11.58 pm

Introduction: What they say A study from Department of Internal Medicine 3-Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany shows that […]

August 18, 2017

Published by admin_auro at August 18, 2017

Categories

Natural product-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing β-Cryptoxanthin, Diindolylmethane (3,3′-DIM, DIM) and Vitamin-D dissolved in Hydrogen-rich water activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan via up regulation of its target gene ATG5 (Autophagy related 5), 18/August/2017, 11.52 pm

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]

August 18, 2017

Published by admin_auro at August 18, 2017

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Natural product-based therapy for TIIDM and obesity-associated metabolic deficits: Geniposide, isolated from Gardenia, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 18/August/2017, 11.27 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that […]

August 18, 2017

Published by admin_auro at August 18, 2017

Categories

Cancer
Ideas

Molecular therapy for Metastatic cancers: Ivermectin, the anthelmintic drug, increases the expression of metastasis suppressors BTG2 and INK4a, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 18/August/2017, 11.03 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]