Ideas

Lifespan extension therapy: Lithocholic acid (LCA) activates autophagy and extend lifespan via up regulation of its target gene, 2/December/2016, 7.04am
Lifespan extension therapy: Lithocholic acid (LCA) activates autophagy and extend lifespan via up regulation of its target gene, 2/December/2016, 7.04am 150 150 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports here that:  Lifespan extension therapy: Lithocholic acid (LCA) activates autophagy and extends lifespan via up regulation of its target gene [easy_payment…

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Molecular therapy for Metabolic disorders: PNUTS (a protein phosphatase) increases (LXR)-α expression, insulin-secreting cell mass and function via down regulation of its target genes, 2/December/2016, 7.01 am
Molecular therapy for Metabolic disorders: PNUTS (a protein phosphatase) increases (LXR)-α expression, insulin-secreting cell mass and function via down regulation of its target genes, 2/December/2016, 7.01 am 150 150 Dr Boomi's Genom-2-Discovery Center

Public health relevance:  Given that (1)  more than 387 million people worldwide are affected by Diabetes mellitus (DM); (2) the life-long painful injection/drug treatment required to treat DM; and (3) the…

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Natural product-derived antiviral therapy against chikungunya (CHIKV) and Zika (ZIKV) viruses: Cucurbitacin E, found abundantly in Watermelons, decreases spermidine/spermine N1-acetyltransferase (SAT1) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 1/December/2015, 8.13 pm
Natural product-derived antiviral therapy against chikungunya (CHIKV) and Zika (ZIKV) viruses: Cucurbitacin E, found abundantly in Watermelons, decreases spermidine/spermine N1-acetyltransferase (SAT1) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 1/December/2015, 8.13 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

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Natural product-based cardioprotective therapy: Lycium barbarum polysaccharide (LBP) increases Spermidine levels, augments autophagy, mitophagy and mitochondrial respiration, lowers systemic blood pressure, and protects it from cardiac diseases via down regulation of its target gene, 1/December/2016, 2.40 pm
Natural product-based cardioprotective therapy: Lycium barbarum polysaccharide (LBP) increases Spermidine levels, augments autophagy, mitophagy and mitochondrial respiration, lowers systemic blood pressure, and protects it from cardiac diseases via down regulation of its target gene, 1/December/2016, 2.40 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute of Molecular Biosciences, University of Graz, Humboldtstraße 50, A-8010 Graz shows that “Cardioprotection and lifespan extension by the natural polyamine spermidine.”…

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Natural product-derived Lifespan extension therapy: EHHM, a natural product found in Livistona chinensis, activates autophagy and extend lifespan via up regulation of its target gene, 1/December/2016, 12.20 pm
Natural product-derived Lifespan extension therapy: EHHM, a natural product found in Livistona chinensis, activates autophagy and extend lifespan via up regulation of its target gene, 1/December/2016, 12.20 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Natural product-derived Lifespan extension therapy: EHHM, a natural product found in Livistona chinensis, activates autophagy and…

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Natural product-derived therapy for Myocardial Infarction: Ferulic acid, found abundantly in the flax seeds, refined maize bran and soft and hard rice bran among others, inhibits DNA damage responses, and telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 1/December/2016, 9.40 am
Natural product-derived therapy for Myocardial Infarction: Ferulic acid, found abundantly in the flax seeds, refined maize bran and soft and hard rice bran among others, inhibits DNA damage responses, and telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 1/December/2016, 9.40 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

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