Ideas

July 6, 2017

Anti-telomerase cancer therapy: CHOP/GADD153 suppresses the expression of Tripeptidyl Peptidase 1 (TPP1) and inhibits cancer progression via down-regulation of it target gene, 6/July/2017, 7.14 am

Introduction: What they say:   The 1989 Nobel prize winner in Chemistry, Prof. Thomas R. Cech from the BioFrontiers Institute, USA has published a research paper in the 13 December 2012 issue of the Nature journal (492(7428):285-9; and I.F: >42) stating that “The TEL patch of telomere protein TPP1 […]
July 6, 2017

Molecular therapy for brain tumor and oesophageal squamous cell carcinoma: Metformin, the widely used drug in the treatment of TIIDM, inhibit the expression of Integrin a7 (ITGA7), impair laminin-induced/FAK mediated signalling, inhibit the proliferation of glioblastoma and oesophageal squamous cell carcinoma stem cells, suppress tumor cell migration, reduce metastasis and prolong survival via down regulation of its target gene, 6/July/2017, 6.58 am

Introduction: What they say: A study from the Institute of General Pathology, Università Cattolica del Sacro Cuore and Fondazione Policlinico Universitario A. Gemelli, 00168 Rome, Italy; Department of Oncology […]
July 5, 2017

Electrical pulse stimulation-based therapy for heart regeneration and repair: Electrical pulse stimulation increases Agrin expression, activates Yap and ERK-mediated signaling, replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 5/July/2017, 11.39 pm

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, Durham, North […]
July 4, 2017

Natural product-derived antiviral therapy against Neuroinvasive West Nile virus: Honokiol, isolated from Magnolia Grandiflora, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 5/July/2017, 1.23 am

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]
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