Ideas

Life-extension therapy: JunB inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 1/December/2016, 6.07 am
Life-extension therapy: JunB inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 1/December/2016, 6.07 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say? A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase…

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Cardiac rejuvenation therapy: SNAI1 , a positive regulator of epithelial-mesenchymal transitions, suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 30/November/2015, 11.14 pm
Cardiac rejuvenation therapy: SNAI1 , a positive regulator of epithelial-mesenchymal transitions, suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy and heart failure via up regulation of its target gene, 30/November/2015, 11.14 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Stem Cell Aging Group, Centro Nacional de Investigaciones Cardiovasculares, E-28029 Madrid, Spain shows that “Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence.” This…

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Natural product-based therapy for Cardiomyopathy: Areca nut extract or Arecoline induces the expression of Trbp/miR-208, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 30/November/2016, 6.59 pm
Natural product-based therapy for Cardiomyopathy: Areca nut extract or Arecoline induces the expression of Trbp/miR-208, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via up regulation of its target gene, 30/November/2016, 6.59 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp…

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Natural product-based cardioprotective therapy: Fisetin, isolated from Strawberry, blueberries, mangoes, apples, persimmon, kiwi, onions, grapes and cucumber among others, increases Spermidine levels, augments autophagy, mitophagy and mitochondrial respiration, lowers systemic blood pressure, and protects it from cardiac diseases via down regulation of its target gene , 30/November/2015, 3.09 pm
Natural product-based cardioprotective therapy: Fisetin, isolated from Strawberry, blueberries, mangoes, apples, persimmon, kiwi, onions, grapes and cucumber among others, increases Spermidine levels, augments autophagy, mitophagy and mitochondrial respiration, lowers systemic blood pressure, and protects it from cardiac diseases via down regulation of its target gene , 30/November/2015, 3.09 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute of Molecular Biosciences, University of Graz, Humboldtstraße 50, A-8010 Graz shows that “Cardioprotection and lifespan extension by the natural polyamine spermidine.”…

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Natural product-derived therapy for Myocardial Infarction: Piceatannol, found in the seeds of passion fruit (Passiflora edulis), inhibits DNA damage responses, and telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 30/November/2016, 9.29 am
Natural product-derived therapy for Myocardial Infarction: Piceatannol, found in the seeds of passion fruit (Passiflora edulis), inhibits DNA damage responses, and telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 30/November/2016, 9.29 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

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Natural product-based therapy for Regenerating the lost cardiomyocytes in Myocardial patients: 2,4,5-trihydroxybenzaldehyde (TDB), found in Geum japonicum and Polygonum cuspidatum (PC), also known as Japanese knotweed, increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 30/November/2016, 5.54 am
Natural product-based therapy for Regenerating the lost cardiomyocytes in Myocardial patients: 2,4,5-trihydroxybenzaldehyde (TDB), found in Geum japonicum and Polygonum cuspidatum (PC), also known as Japanese knotweed, increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes via down regulation of its target gene, 30/November/2016, 5.54 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was…

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