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Ideas

March 5, 2017

Natural product-based therapy for Metastatic cancers: Hyperoside, isolated from Drosera rotundifolia, and Common self-heal, among others, increases the expression of KRIT1/CCM1 and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 5/March/2017, 10.54 pm

Research findings to Therapeutic opportunity:  A number of studies suggest that Hyperoside functions as an anticancer agent. However, the mechanism of action is far from clear. […]
March 5, 2017

Molecular therapy for Metastatic cancers: Piper betle leaf extract decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up regulation of its target gene, 5/March/2017, 10.30 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
March 4, 2017

Natural product-derived therapy for glucose homeostasis and TIIDM: Polydatin (PD), a longevity-promoting molecule isolated from Polygonum cuspidatum, increases Barr2 expression, augments the functional activity of CAMKII, increases insulin secretion, promotes glucose homeostasis, prevents progression to TIIDM and ameliorates obesity-associated metabolic deficits via down regulation of its target gene, 4/March/2017, 11.51 pm

Introduction: What they say A study from the Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland […]
March 4, 2017

Vitamin-based therapy for metastatic prostate cancer: Cholecalciferol inhibits the expression of CDC42, CDC42EP3, RAC1 and ARPC5, and GAS6, suppresses the expression of stem cell molecules CD44 and EZH2, promotes epithelial phenotype, suppresses tumorigenesis, migration, invasion, stem cell regeneration and metastasis via up regulation of its target gene, 4/March/2017, 11.17 pm

Introduction: What they say: A study from the Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Science Park, Texas 78957, USA […]
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