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April 21, 2017
Published by admin_auro at April 21, 2017
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Natural product-derived PD-L1 pathway blockade enhances the efficacy of Cancer immunotherapy: Marrubium vulgare extract inhibits the expression of PD-L1, inhibits inflammatory signalling and the number of tumor-infiltrating lymphocytes and macrophages, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 21/April/2017, 10.15 pm

Introduction:What they say: A recent study from Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Unit 108, 1515 Holcombe Boulevard, […]
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April 21, 2017
Published by admin_auro at April 21, 2017
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Antiviral therapy for HIV virus: 15-Deoxy-Δ12,14 Prostaglandin J2 (15d-PGJ2) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 21/April/2017, 4.03 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Antiviral therapy for HIV virus: 15-Deoxy-Δ12,14 Prostaglandin J2 (15d-PGJ2) increases Heme oxygenase 2 (HO-2) expression, […]
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April 21, 2017
Published by admin_auro at April 21, 2017
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Natural product-derived PD-1 pathway blockade for Human cancer therapy: Nectandrin B, isolated from Nutmeg, decreases the activity of Glycogen synthase kinase-3β, increases transcription factor T-bet expression, decreases the abundance of co-inhibitory receptor PD-1 on the cell surface of Cytotoxic-T-cells, increases cytotoxic T lymphocyte function and augments anti-tumor activity, via up-regulation of its target gene, 21/April/2017, 6.21 am

Introduction:What they say:  A recent study from Cell Signalling Section, Division of Immunology, Department of Pathology, Tennis Court Road, University of Cambridge, Cambridge CB2 1QP, UK […]
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April 20, 2017
Published by admin_auro at April 20, 2017
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Natural product-derived therapy therapy for Stroke: Nectandrin B, a Nutmeg lignan, attenuates hippocampal neurons injury and ameliorates stroke damage and neurological deficits via up regulation of its target gene BDNF., 20/April/2017, 11.13 pm

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]
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