Ideas

Molecular therapy for Myocardial Infarction: Long ncRNA NEAT improves myocardial function after myocardial infarction via up-regulation of PNUTS, 27/November/2016, 10.14 pm
Molecular therapy for Myocardial Infarction: Long ncRNA NEAT improves myocardial function after myocardial infarction via up-regulation of PNUTS, 27/November/2016, 10.14 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What…

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Antimetastasis therapy: MiRNA-9600 increases the expression of tumor suppressor long ncRNA GAS5 and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 27/November/2016, 8.29 pm
Antimetastasis therapy: MiRNA-9600 increases the expression of tumor suppressor long ncRNA GAS5 and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 27/November/2016, 8.29 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Research findings to Therapeutic opportunity:  The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may increase the expression of tumor suppressor long ncRNA GAS5. [easy_payment…

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Anti-metastasis therapy: Tumor suppressor ING1b/p33 decreases PDPN expression, invasion, migration and metastasis of tumor cells via up regulation of its target gene, 27/November/2015, 8.16 pm
Anti-metastasis therapy: Tumor suppressor ING1b/p33 decreases PDPN expression, invasion, migration and metastasis of tumor cells via up regulation of its target gene, 27/November/2015, 8.16 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Research findings to Therapeutic opportunity:  The study presented here suggests that tumor suppressor ING1b/p33, by increasing the expression of its target genes, it may decrease the expression of oncoprotein PDPN. Thereby,…

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Molecular therapy for Bone disorders: MiR-188 inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 27/November/2016, 8.10 pm
Molecular therapy for Bone disorders: MiR-188 inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 27/November/2016, 8.10 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis…

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Molecular therapy for KRAS-mutant lung cancer: UBTD1 (Ubiquitin domain containing 1) decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene, 27/November/2016, 8.03 pm
Molecular therapy for KRAS-mutant lung cancer: UBTD1 (Ubiquitin domain containing 1) decreases the expression of XPO1, increases the level of NFKBIA, inhibits NFKB transcriptional activity and suppresses the progression of KRAS-mutant lung cancer via up regulation of its target gene, 27/November/2016, 8.03 pm 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Department of Cell Biology, University of Texas Southwestern Medical Center, Texas 75390, USA shows that XPO1 can be pharmacologically targeted in KRAS-mutant lung cancer.…

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Molecular therapy for Intestinal cancer: JunD increases the expression of DNA Sensor AIM2 and inhibits expansion of tumor-initiating intestinal stem cell population via up regulation of its target gene, 27/November/2016, 8.38 am
Molecular therapy for Intestinal cancer: JunD increases the expression of DNA Sensor AIM2 and inhibits expansion of tumor-initiating intestinal stem cell population via up regulation of its target gene, 27/November/2016, 8.38 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say: Introduction: A recent study from the Department of Immunology, Saint Jude Children’s Research Hospital, Memphis, TN 38105, USA shows that:  “Critical Role for the DNA Sensor AIM2 in…

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