Ideas

Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Long ncRNA CCAT1 promotes an insulin-sensitized state via up-regulation of reprogramming protein Lin28, 27/November/2016, 6.39 am

Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Long ncRNA CCAT1 promotes an insulin-sensitized state via up-regulation of reprogramming protein Lin28, 27/November/2016, 6.39 am 150 150 Dr Boomi's Genom-2-Discovery Center

What we say:  On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Molecular therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Long ncRNA CCAT1 promotes an insulin-sensitized…

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Molecular therapy for Bone disorders: MiR-7-3p inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 26/November/2016, 6.04 pm

Molecular therapy for Bone disorders: MiR-7-3p inhibits the expression of Tgif2 and suppresses osteoporosis and bone metastasis via up-regulation of its target gene, 26/November/2016, 6.04 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA has reported that “miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis…

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MiRNA-based PD-1 pathway blockade for Human cancer therapy: MiR-24-3p inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 26/November/2016, 5.56 pm

MiRNA-based PD-1 pathway blockade for Human cancer therapy: MiR-24-3p inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 26/November/2016, 5.56 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say:  A recent study from Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD 21218, United States shows that “TGF-β1-Mediated Smad3 Enhances PD-1 Expression on…

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Molecular therapy for Myocardial Infarction: MiR-27a improves myocardial function after myocardial infarction via up-regulation of PNUTS, 25/November/2016, 11.06 pm

Molecular therapy for Myocardial Infarction: MiR-27a improves myocardial function after myocardial infarction via up-regulation of PNUTS, 25/November/2016, 11.06 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What…

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MiRNA-based PD-1 pathway blockade for Human cancer therapy: MiR-328 inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 25/November/2016, 10.46 pm

MiRNA-based PD-1 pathway blockade for Human cancer therapy: MiR-328 inhibits the expression of co-inhibitory receptor PD-1 on Antigen- Specific T-cells, increases the production of cytokines by tumor-infiltrating lymphocytes (TIL), and draining lymph nodes and augments anti-tumor activity via down-regulation of its target gene, 25/November/2016, 10.46 pm 150 150 Dr Boomi's Genom-2-Discovery Center

[easy_payment currency=”USD”] Introduction:What they say:  A recent study from Division of Infectious Diseases, School of Medicine, Johns Hopkins University, Baltimore, MD 21218, United States shows that “TGF-β1-Mediated Smad3 Enhances PD-1…

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Natural product-derived anti-ageing therapy: Shikonin, the major component of Zicao (also known as purple gromwell, the dried root of Lithospermum erythrorhizon), increases NMN levels, decreases age-associated weight gain, augments energy metabolism, improves physical activity and insulin sensitivity, promotes healthy lipid profile, and improves eye function via down regulation of its target gene, 25/November/2015, 10.33 pm

Natural product-derived anti-ageing therapy: Shikonin, the major component of Zicao (also known as purple gromwell, the dried root of Lithospermum erythrorhizon), increases NMN levels, decreases age-associated weight gain, augments energy metabolism, improves physical activity and insulin sensitivity, promotes healthy lipid profile, and improves eye function via down regulation of its target gene, 25/November/2015, 10.33 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Gladstone Institute of Neurological Disease and Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA and Department of Developmental…

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