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Ideas

February 24, 2017

Natural product-derived therapy for Myocardial Infarction: Morin (3,5,7,2′,4′-pentahydroxyflavone), found in Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and leaves of Psidium guajava (common guava), inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 24/February/2017, 6.40 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, […]
February 24, 2017

Natural product-derived Anti-AXL therapeutics for enhancing the efficacy of chemotherapies: Combination of Diallyl trisulfide and Baicalein, found in Garlic and Scutellaria baicalensis, respectively, decreases the expression of the AXL receptor and its activating ligand, GAS6, increases the expression of a number of tumor suppressor genes, increases therapeutic index of anticancer drugs, suppresses tumorigenesis, migration, invasion, and metastasis via up regulation of its target gene, 24/February/2017, 6.04 am

Introduction: What they say: A study from the Department of Radiation Oncology, Stanford University School of Medicine shows that “Inhibition of the GAS6/AXL pathway augments the […]
February 23, 2017

Natural product-derived therapy for glucose homeostasis and TIIDM: Morin (3,5,7,2′,4′-pentahydroxyflavone), found in Maclura pomifera (Osage orange), Maclura tinctoria (old fustic) and leaves of Psidium guajava (common guava), increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of their target gene, 23/February/2017, 11.49 pm

Introduction: What they say  A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, […]
February 23, 2017

Natural product-derived Anti-AXL therapeutics for enhancing the efficacy of chemotherapies: Combination of Valproic acid and Deoxycholic acid, decreases the expression of the AXL receptor and its activating ligand, GAS6, increases the expression of a number of tumor suppressor genes, increases therapeutic index of anticancer drugs, suppresses tumorigenesis, migration, invasion, and metastasis via up regulation of its target gene, 23/February/2017, 10.38 pm

Introduction: What they say: A study from the Department of Radiation Oncology, Stanford University School of Medicine shows that “Inhibition of the GAS6/AXL pathway augments the […]
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