Ideas

Molecular therapy for Metabolic disorders: MiRNA-183 increases liver-X-receptor expression, protects aganist diet-induced weight-gain, and increases insulin-secreting cell mass and function via down regulation of its target genes, 20/November/2016, 10.30 am
Molecular therapy for Metabolic disorders: MiRNA-183 increases liver-X-receptor expression, protects aganist diet-induced weight-gain, and increases insulin-secreting cell mass and function via down regulation of its target genes, 20/November/2016, 10.30 am 150 150 Dr Boomi's Genom-2-Discovery Center

Significance of the study:  Given that (1)  more than 387 million people worldwide are affected by Diabetes mellitus (DM); (2) the life-long painful injection/drug treatment required to treat DM; and (3)…

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Molecular therapy for tuberculosis: MiRNA-128-1 increases the expression of MKP-1, inhibits TLR2 signalling, secretion of Chemokine CXCL5, and recruitment of polymorphonuclear leukocytes (PMNs), decreases destructive pulmonary inflammation, promotes M. tuberculosis clearance and inhibits pulmonary tuberculosis via up-regulation of its target gene, 20/November/2016, 10.01 am
Molecular therapy for tuberculosis: MiRNA-128-1 increases the expression of MKP-1, inhibits TLR2 signalling, secretion of Chemokine CXCL5, and recruitment of polymorphonuclear leukocytes (PMNs), decreases destructive pulmonary inflammation, promotes M. tuberculosis clearance and inhibits pulmonary tuberculosis via up-regulation of its target gene, 20/November/2016, 10.01 am 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Max Plank Institute for Infection Biology, Berlin, Germany shows that “CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis.” This study was…

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Anti-metastasis therapy: MiRNA-9600 increases the expression of Metastasis suppressor TIMP3 (TIMP Metallopeptidase Inhibitor 3) and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 20/November/2015, 9.09 am
Anti-metastasis therapy: MiRNA-9600 increases the expression of Metastasis suppressor TIMP3 (TIMP Metallopeptidase Inhibitor 3) and inhibits migration, invasion and metastasis of cancer cells via down regulation of its target gene, 20/November/2015, 9.09 am 150 150 Dr Boomi's Genom-2-Discovery Center

Research findings to Therapeutic opportunity:  The study presented here suggests that MiRNA-9600, by decreasing the expression of its target genes, it may increase the expression of Matrix metalloproteinases inhibitor TIMP3. Thereby, it…

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Natural product Life-extension therapy: Moringa oleifera (MO) extract inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 20/November/2016, 8.51 am
Natural product Life-extension therapy: Moringa oleifera (MO) extract inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 20/November/2016, 8.51 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say? A recent study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase…

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Natural product therapy for Myocardial Infarction: Puerarin, an isoflavone found in Pueraria (Radix puerariae), improves myocardial function after myocardial infarction via up-regulation of PNUTS, 20/November/2016, 8.24 am
Natural product therapy for Myocardial Infarction: Puerarin, an isoflavone found in Pueraria (Radix puerariae), improves myocardial function after myocardial infarction via up-regulation of PNUTS, 20/November/2016, 8.24 am 150 150 Dr Boomi's Genom-2-Discovery Center

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published in the 7 March  2013 issue of Nature  by Prof Dimmler, Boon, and others. What we…

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Molecular therapy for tuberculosis: MiRNA-429 increases the expression of MKP-1, inhibits TLR2 signalling, secretion of Chemokine CXCL5, and recruitment of polymorphonuclear leukocytes (PMNs), decreases destructive pulmonary inflammation, promotes M. tuberculosis clearance and inhibits pulmonary tuberculosis via up-regulation of its target gene, 19/November/2016, 10.23 pm
Molecular therapy for tuberculosis: MiRNA-429 increases the expression of MKP-1, inhibits TLR2 signalling, secretion of Chemokine CXCL5, and recruitment of polymorphonuclear leukocytes (PMNs), decreases destructive pulmonary inflammation, promotes M. tuberculosis clearance and inhibits pulmonary tuberculosis via up-regulation of its target gene, 19/November/2016, 10.23 pm 150 150 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:  A study from the Max Plank Institute for Infection Biology, Berlin, Germany shows that “CXCL5-secreting pulmonary epithelial cells drive destructive neutrophilic inflammation in tuberculosis.” This study was…

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