Ideas

August 8, 2017

 Lifespan extension therapy: Avermectin, the parent of anti-parasitic drug Ivermecitin, activates autophagy and extends lifespan via up regulation of ATG5, 9/August/2017, 12.46 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
August 7, 2017

Natural product-derived PD-1 pathway activation for Pain therapy: Pyrroloquinoline quinone (PQQ), isolated from Kiwisfruits, increases the expression of PD-L1, attenuates acutes and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability via up-regulation of its target gene, 8/August/2017, 12.57 am

Introduction:What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for Brain […]
August 7, 2017

Natural product-derived therapy for Stroke: Pyrroloquinoline quinone (PQQ), isolated from kiwifruit, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 7/August/2017, 9.50 pm

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]
August 7, 2017

Molecular therapy for anxiety and depression:  Amitriptyline (Brand name: Elavil) decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression via down regulation of its target gene, 7/August/2017, 9.40 pm

Introduction: What they say: A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
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