A sweet way to say no to Autoimmune diabetes (TIDM): Sugar-based therapy for autoimmune diabetes (TIDM): Trehalose, a natural sweetener isolated from mushrooms among others,  increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 16/March/2018, 7.20 am