A study from Division of Cellular and Developmental Biology, MCB Department, University of California at Berkeley, Berkeley, California, USA has reported that “miR-34/449 miRNAs are required for motile ciliogenesis by..”
This study was published in the 04 June 2014 Nature (IF: 38.597) by Prof. Lin He, Song Rui and others from Division of Cellular and Developmental Biology, MCB Department, University of California at Berkeley, Berkeley, California, USA.
On the foundation of this interesting finding, Dr L Boominathan, Director-cum-chief Scientist of GBMD, reports here that: Mechanistic & Therapeutic insights into Motile Ciliogenesis & Respiratory dysfunction (Primary cilia dyskinesia): δ-tocotrienol (A derivative of Vitamin-E) increases Cilia length and number via up regulation of its target gene. This study suggests that derivatives of Vitamin-E may alleviate respiratory dysfunction that is commonly found in disease conditions such as Primary cilia dyskinesia. Together, this study suggests that pharmacological formulations encompassing “derivatives of Vitamin-E“ can be used, either alone, or in combination with other drugs, to treat Primary cilia dyskinesia.
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Web: http://genomediscovery.org
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
To cite: Boominathan, Mechanistic & Therapeutic insights into Motile Ciliogenesis & Respiratory dysfunction (Primary cilia dyskinesia): δ-tocotrienol (A derivative of Vitamin-E) increases Cilia length and number via up regulation of its target gene, 26/July/2014, 6.55 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Courtesy: When you cite drop us a line at info@genomediscovery.org
* Research cooperation
