Conference Publications/Posters
- Boominathan L, and Kanaga S, c-Jun is required for stabilization and activation of the p53-homologue, p73, 5th Beatson International Cancer Conference (sponsored by AARC), Glasgow, UK, from July 15th to 18th, 2001. Beatson cancer conference booklet cover0001; and Beatson International Cancer Conference0001
- Boominathan L, and Kanaga S, UV and Cisplatin-mediated p73 stabilization and p53-independent apoptosis require c-Jun. International p53 Workshop, Barcelona, Spain, from May 15to 18th , 2002.International p53 workshop bookelt cover0001; UV.Cisplatin mediate p73 stabilization Int p53 workshop0001; c.Jun stabilizes p73, poster presented at the Internatioanal p53 workshop; and c-Jun stabilizes p73 protein-poster International p53 workshop
- Kanaga S., Boominathan L, Vasantha MN, Lin K.W, UV-mediated p73 stabilization, resulting in p53-independent apoptosis.11th International p53 Workshop, Barcelona, Spain, from May 15to 18th , 2002.UV-mediated p73 stabilization, Int. p53 workshop0001
- Kanaga S and Boominathan L c-Jun is required for stabilization and activation of the p53-homologue, p73. 1st International p63/p73 workshop 2002, Rome, Italy, from June 10to11th, 2002.c-Jun promotes p73 stability p63.p73 workshop0001; and p63.p73 workshop cover page0001
- Kanaga S and Boominathan L, c-Jun is required for stabilization and activation of the p53-homologue, p73, Cancer Genetics & Tumor Suppressor Genes, Cold spring harbor laboratory, NY, USA, from August 14 –18th, 2002. (Data presented in Poster no. 1 to 5 form the basis for obtaining an International patent —http://www.google.com/patents/US20060127895?printsec=description&dq=Jun+p73&ei=bPXmT5jJOszIrQfc2ZT5CA#v=onepage&q=Jun%20p73&f=false—by the Group leader. Its utility estimated to be in the range of one billion American dollars/year. To quote their own words, “The potential market for such a drug could easily be in excess of US$ ONE billion/year.” Reference : The Market value of Patent applied during Dr Boominathan’s tenure at NCC Singapore)
- L Boominathan p63, p73, and p53 are negative regulators of EMT, invasion and metastasis AICBC & International workshop on cell cycle regulation, 2009, Hyderabad, India.
- L Boominathan The guardians of the genome dependent tumor suppressor miRNAs networkAICBC & International workshop on cell cycle regulation, 2009, Hyderabad, India.
- L Boominathan Curcumin functions as a positive regulator of miRNA processing and a negative regulator of cancer stem cell proliferation. Indo-US work shop on “Epigenetics and genomic regulation (with emphasis on RNAi & miRNA)”, 2009, Hyderabad, India.
- L Boominathan Tumor suppressors function as a bottleneck against cellular reprogramming into iPS cells, International conference on Emerging trends in Biotechnology, 2009, Varanasi, India.
- L Boominathan p53, p73, and p63 regulate alternative splicing by regulating components of Spliceosome machinery through their target miRNAs International Symposium on Frontiers in Carcinogenesis and Cancer prevention: Scientific endeavours and Public health initiatives, 2010, Mumbai, India.
- L Boominathan The p73 functions as a Lung tumor suppressor by increasing the expression of miRNA, let-7 International conference in Cancer biology: Molecular mechanisms & therapeutics, 2010, Chennai, India
- L Boominathan Molecular Mechanistic insights into p73 and p63’s ability to function as tumor suppressors International conference in Cancer biology: Molecular mechanisms & therapeutics, 2010, Chennai, India.
- L Boominathan p53, p73, and p63 inhibit Leukemic stem cell development through their target miRNAs 29th Annual Convention of Indian association of cancer research and Symposium on Biology of Cancer Stem cells, 2010, Cochin, India.
- L Boominathan p53, p63, and p73 inhibit migrating cancer stem cells by activating stem cell suppressing miRNAs 29th Annual Convention of Indian association of cancer research and Symposium on Biology of Cancer Stem cells, 2010, Cochin, India.
- L Boominathan p73/p63/p53 functions as a mitotic checkpoint by negatively regulating AURKs and PLKs through its target miRNAs 29thAnnual Convention of Indian association of cancer research and Symposium on Biology of Cancer Stem cells, 2010, Cochin, India.
- L Boominathan The TA-p73/p63 functions as a lung/leukemia tumor suppressor by increasing the expression of Downstream of Tyrosine Kinases genes. International conference on frontiers in biological sciences (InCoFIBS) 2010, Rourkela, India.
- L Boominathan Cigarette smoking represses p53/p73/p63-miRNAs that suppress cancer stem cell (CSC) proliferation, and increases miRNAs that promote CSC proliferation. International Conference on Stem cells and Cancer (ICSCC-2010), Pune, India.
- L Boominathan p53 and TA-p73/p63 regulate components of the epigenetic machinery through their target miRNAs. International Conference on Stem cells and Cancer (ICSCC-2010), Pune, India.
- L Boominathan Activator protein-1 controls tumorigenesis, reprogramming, and CSC proliferation by regulating Lin-28-let-7 feedback circuit International Conference on Stem cells and Cancer (ICSCC-2010), Pune, India.
- L Boominathan Mechanisms through which p63/p73 functions as a tumor suppressor, Annual Convention of Indian Association of Cancer Research and Interanational symposium on Signalling network and cancer (IACR)-2011, Kolkata, India.
- L Boominathan Guardians of the genome (p53/p73/p63) function as regulators of happiness/depression Frontiers in Carcinogenesis and Cancer Prevention: Scientific Advances and Public Health Initiatives, 2011, Bangalore, India
- L Boominathan p53/p63/p73-miRNAs function as Judges: Deciding between G1/G2-M phase arrest versus apoptosis International Conference on Stem cells and Cancer (ICSCC-2011), Pune, India.
- L Boominathan Guardians of the genome-p53, p63, and p73-function as regulators of Sleeping pattern and depression International Conference on Stem cells and Cancer (ICSCC-2011), Pune, India.
- L Boominathan Connection between the stress-induced oncosuppressor protein, p53 (p63/p73) and a regulator of pluripotency, lin-28 in controlling the initiation of diabetes International Conference on Stem cells and Cancer (ICSCC-2011), Pune, India.
Abstracts:
- L. Boominathan, p53 family tumor suppressor network links multiple tumor suppressor pathways: p63/p73-dependent tumor suppressor pathways. The Eighth International Conference of Anti-cancer research October 17-22, 2008 Kos, Greece. EIGHTH INTERNATIONAL CONFERENCE of anticancer research
- L Boominathan The concept of tumorsuppressome 29th Annual Convention of Indian association of cancer research and Symposium on Biology of Cancer Stem cells, 2010, Cochin, India.
- L Boominathan The tumor suppressors p73, p63 and p53 regulate asymmetric cell division and spindle-check point 29th Annual Convention of Indian association of cancer research and Symposium on Biology of Cancer Stem cells, 2010, Cochin, India.
- L Boominathan The tumor suppressors p53, TA-p73 and TA-p63 inhibit the expression of ∆NEx2p73 and ∆N-p63 through their target miRNAs International Symposium on Bioinformatics, 2010, Gujarat, India
- L Boominathan Molecular insight into Curcumin’s ability to function as an Anti-cancer/Inflammatory agent: Curcumin regulates Toll signaling through its targets p53/p73/p63, ATF3, and miRNAs International Symposium on Bioinformatics, 2010, Gujarat, India
- L Boominathan p53/TAp63/p73 regulates c-Jun and c-fos family through its target miRNAs International Symposium on Bioinformatics, 2010, Gujarat, India.
- L Boominathan p53/TA-p63/p73 regulates c-Jun NH2-terminal kinase signal transduction pathway through its target miRNAs, AICB conference, 2010, Kolkata, India.