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Idea Proposed/Formulated byDr L Boominathan Ph.D.

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CitationBoominathan, Mechanistic and Therapeutic insights into Why heart attack occurs more during winter: Cold temperature inhibits cardiac reprogramming by down regulating cardiac protetive gene, 09/September/2014, 11.48 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org

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Significance: This study provides, for the first time, a molecular explanation as to why there are more heart attacks during winter. Furthermore, this study has identified a gene that is responsible for poor performance of cardiomyocytes during the winter.  Thus, pharmacological formulations encompassing “Cold temperature-down regulated gene or its small molecule activator” may be used to  protect one from heart attack during the winter and improve cardiac performance.

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