Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Web: http://genomediscovery.org
Terms & Conditions apply http://genomediscovery.org/registration/terms-and-conditions/
To cite: Boominathan, MiRNA-based Cancer therapeutics: MiRNA-382 increases the expression of the guardian of the genome p53 via down regulation of its target gene, 11/October/2014, 8.54 am, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
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* Research cooperation
Significance: This study suggests that miR-382, by suppressing the expression of its target gene, it may increase the transcription of tumor suppressor p53. Furthermore, this study suggests a therapeutic strategy as to how human cancers with intact p53 can be treated. Together, pharmacological formulations encompassing “MiRNA-382 activators” may be used to treat human tumors with intact p53.
