Genome-2-Bio-Medicine Discovery center founder’s father’s (teacher) death anniversary day-26th May
*********
On the eve of Genome-2-Bio-Medicine Discovery center founder’s father’s (teacher) death anniversary day, we wish to inform you that the ideas posted today (26/May/2015) will be available to the use of Scientists/Professors/Teachers/Physicians/Researchers for free. So, there will be no terms and conditions for the ideas posted today (26/May/2015). Each idea posted will be served first come, first served basis.Write to info@genomediscovery.org for more details.
Dr L Boominathan PhD
President & CSO, GBMD.
*********************************************************************************************
Idea Proposed/Formulated by: Dr L Boominathan Ph.D.
Citation: Boominathan, L., Small molecule-based Lifespan extension therapy: Plumbagin, isolated from the roots of herb Plumbaginaceae, may prolong mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 26/May/2015, 23.07, Genome-2-Bio-Medicine Discovery center (GBMD), http://genomediscovery.org
Web: http://genomediscovery.org
Courtesy: When you cite drop us a line at info@genomediscovery.org
Significance: It has been shown earlier that angiotensin II type I receptor (AT1R) antagonist prolongs mammalian life span. This study suggests, for the first time, that Plumbagin , by increasing the expression of its target gene, it may suppress the expression of AT1R. And, thereby, it may (1) decrease blood pressure; (2) decrease blood sugar levels; (3) decrease ageing; and (4) extend the lifespan of an individual. Thus, pharmacological formulations encompassing “Plumbagin or its analogues” may be used to extend the life-span of an individual.
Undisclosed information: How Plumbagin suppresses the expression of angiotensin II type I receptor (AT1R)
